产品内容
本酶催化的反应为Cholest-4-En-3-One + 3 NADPH + 3 H+ + 3 O2 = (25R)-3-Oxocholest-4-En-26-Oate + 3 NADP+ + 4 H2O (Overall Reaction);;(1a) Cholest-4-En-3-One + NADPH + H+ + O2 = (25R)-26-Hydroxycholest-4-En-3-One + NADP+ + H2O;;(1b) (25R)-26-Hydroxycholest-4-En-3-One + NADPH + H+ + O2 = (25R)-26-Oxocholest-4-En-3-One + NADP+ + 2 H2O;;(1c) (25R)-26-Oxocholest-4-En-3-One + NADPH + H+ + O2 = (25R)-3-Oxocholest-4-En-26-Oate + NADP+ + H2O，系统名称为Cholest-4-En-3-One,NADPH:oxygen Oxidoreductase [(25R)-3-Oxocholest-4-En-26-Oate Forming]，该酶存在于几种细菌病原体中，参与宿主胆固醇的降解。它催化C-26碳的羟化，随后经醛中间体将醇氧化为羧酸，启动胆固醇烷基侧链的降解。产物完全为(25R)构型。该酶也接受胆固醇作为底物。参见 EC 1.14.13.141，胆甾-4-烯-3-酮26-单加氧酶。该酶在体外可从铁氧还蛋白还原酶接收电子，其天然电子供体尚不清楚。
![天净沙胆甾-4-烯-3-酮26-单加氧酶[生成(25R)-3-氧代胆甾-4-烯-26-酸型]活性测定试剂盒产品图片](https://www.tjs.bio/content/xtheme/tianjingsha/images/noimage.jpg)
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