产品内容
本酶催化的反应为Aurachin C + NAD(P)H + H+ + O2 = 4-Hydroxy-2-Methyl-3-Oxo-4-[(2E,6E)-Farnesyl]-3,4-Dihydroquinoline 1-Oxide + NAD(P)+ + H2O (Overall Reaction);;(1a) Aurachin C + NAD(P)H + H+ + O2 = 2-Hydroxy-1A-Methyl-7A-[(2E,6E)-Farnesyl]-1A,2-Dihydrooxireno[2,3-B]quinolin-7(7AH)-One + NAD(P)+ + H2O;;(1b) 2-Hydroxy-1A-Methyl-7A-[(2E,6E)-Farnesyl]-1A,2-Dihydrooxireno[2,3-B]quinolin-7(7AH)-One = 4-Hydroxy-2-Methyl-3-Oxo-4-[(2E,6E)-Farnesyl]-3,4-Dihydroquinoline 1-Oxide，系统名称为Aurachin C:NAD(P)H:oxygen Oxidoreductase (4-Hydroxy-2-Methyl-3-Oxo-4-Farnesyl-3,4-Dihydroquinoline-1-Oxide-Forming)，来自细菌橙色标桩菌 Stigmatella aurantiaca 的金链菌素C单加氧酶既可利用NADH也可利用NADPH作为辅因子，但更偏好NADH。它催化金链菌素C转化为金链菌素B的起始步骤。这种依赖FAD的单加氧酶催化金链菌素C C2-C3双键的环氧化，随后发生半频哪醇重排，使法尼基从C3迁移到C4。
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