产品内容
本酶催化的反应为Germacra-1(10),4,11(13)-Trien-12-Oate + [Reduced NADPH---Hemoprotein Reductase] + O2 = 8-Epi-Inunolide + [Oxidized NADPH---Hemoprotein Reductase] + 2 H2O (Overall Reaction);;(1a) Germacra-1(10),4,11(13)-Trien-12-Oate + [Reduced NADPH---Hemoprotein Reductase] + O2 = 8alpha-Hydroxygermacra-1(10),4,11(13)-Trien-12-Oate + [Oxidized NADPH---Hemoprotein Reductase] + H2O;;(1b) 8alpha-Hydroxygermacra-1(10),4,11(13)-Trien-12-Oate = 8-Epi-Inunolide + H2O (Spontaneous),系统名称为Germacra-1(10),4,11(13)-Trien-12-Oate,[reduced NADPH---Hemoprotein Reductase]:oxygen Oxidoreductase (8alpha-Hydroxylating),一种来自湖北旋覆花(Inula hupehensis)的细胞色素 P-450(血红素-硫醇盐)蛋白。该酶还产生 8β-羟基吉马烯-1(10),4,11(13)-三烯-12-酸(EC 1.14.14.168,吉马烯 A 酸 8β-羟化酶)。