产品内容
本酶催化的反应为A Long-Chain Acyl-[Acyl-Carrier Protein] + 2 Reduced Flavodoxin + 3 O2 = Pimeloyl-[Acyl-Carrier Protein] + An N-Alkanal + 2 Oxidized Flavodoxin + 3 H2O (Overall Reaction);;(1a) A Long-Chain Acyl-[Acyl-Carrier Protein] + Reduced Flavodoxin + O2 = A (7S)-7-Hydroxy-Long-Chain-Acyl-[Acyl-Carrier Protein] + Oxidized Flavodoxin + H2O;;(1b) A (7S)-7-Hydroxy-Long-Chain-Acyl-[Acyl-Carrier Protein] + Reduced Flavodoxin + O2 = A (7R,8R)-7,8-Dihydroxy-Long-Chain-Acyl-[Acyl-Carrier Protein] + Oxidized Flavodoxin + H2O;;(1c) A (7R,8R)-7,8-Dihydroxy-Long-Chain-Acyl-[Acyl-Carrier Protein] + Reduced Flavodoxin + O2 = A 7-Oxoheptanoyl-[Acyl-Carrier Protein] + An N-Alkanal + Oxidized Flavodoxin + 2 H2O;;(1d) A 7-Oxoheptanoyl-[Acyl-Carrier Protein] + Oxidized Flavodoxin + H2O = A Pimeloyl-[Acyl-Carrier Protein] + Reduced Flavodoxin + H+，系统名称为Acyl-[Acyl-Carrier Protein],reduced-Flavodoxin:oxygen Oxidoreductase (Pimeloyl-[Acyl-Carrier Protein] Forming)，血红素-硫醇盐蛋白（P-450）。该酶催化各种链长的长链酰基-[酰基载体蛋白]的氧化性 C-C 键断裂，生成庚二酰-[酰基载体蛋白]，一种生物素生物合成的中间体。来自枯草芽孢杆菌 Bacillus subtilis 的酶的优先底物是棕榈酰-[酰基载体蛋白]，随后生成庚醛作为烷醛。其机制类似于 EC 1.14.15.6 胆固醇单加氧酶（侧链断裂），随后是一步可能自发发生的羟化 [2]。
![天净沙庚二酰-[酰基载体蛋白]合酶活性测定试剂盒产品图片](https://www.tjs.bio/content/xtheme/tianjingsha/images/noimage.jpg)
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