产品内容
本酶催化的反应为Cholest-4-En-3-One + 6 Reduced [2Fe-2S] Ferredoxin + 3 O2 = (25R)-3-Oxocholest-4-En-26-Oate + 6 Oxidized [2Fe-2S] Ferredoxin + 4 H2O (Overall Reaction);;(1a) Cholest-4-En-3-One + 2 Reduced [2Fe-2S] Ferredoxin + O2 = (25R)-26-Hydroxycholest-4-En-3-One + 2 Oxidized [2Fe-2S] Ferredoxin + H2O;;(1b) (25R)-26-Hydroxycholest-4-En-3-One + 2 Reduced [2Fe-2S] Ferredoxin + O2 = (25R)-26-Oxocholest-4-En-3-One + 2 Oxidized [2Fe-2S] Ferredoxin + 2 H2O;;(1c) (25R)-26-Oxocholest-4-En-3-One + 2 Reduced [2Fe-2S] Ferredoxin + O2 = (25R)-3-Oxocholest-4-En-26-Oate + 2 Oxidized [2Fe-2S] Ferredoxin + H2O，系统名称为Cholest-4-En-3-One,reduced [2Fe-2S] Ferredoxin:oxygen Oxidoreductase [(25R)-3-Oxocholest-4-En-26-Oate-Forming]，这种细胞色素 P-450（血红素-硫醇盐）酶存在于若干细菌病原体中，参与宿主胆固醇的降解。它催化 C-26 碳的羟基化，随后经醛中间体将醇氧化为羧酸，启动胆固醇烷基侧链的降解。产物仅为 (25R) 构型。该酶也接受胆固醇作为底物。参见 EC 1.14.15.29（胆甾-4-烯-3-酮 26-单加氧酶 [(25S)-3-氧代胆甾-4-烯-26-酸形成型]）。体外该酶可从铁氧还蛋白还原酶获得电子，其天然电子供体尚不清楚。
![天净沙胆甾-4-烯-3-酮26-单加氧酶[(25R)-3-氧代胆甾-4-烯-26-酸形成]活性测定试剂盒产品图片](https://www.tjs.bio/content/xtheme/tianjingsha/images/noimage.jpg)
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