产品内容
本酶催化的反应为(1) Narbomycin + 2 Reduced Ferredoxin [Iron-Sulfur] Cluster + 2 H+ + O2 = Pikromycin + 2 Oxidized Ferredoxin [Iron-Sulfur] Cluster + H2O;;(2) Narbomycin + 2 Reduced Ferredoxin [Iron-Sulfur] Cluster + 2 H+ + O2 = Neopikromycin + 2 Oxidized Ferredoxin [Iron-Sulfur] Cluster + H2O;;(3) Narbomycin + 4 Reduced Ferredoxin [Iron-Sulfur] Cluster + 4 H+ + 2 O2 = Novapikromycin + 4 Oxidized Ferredoxin [Iron-Sulfur] Cluster + 2 H2O;;(4) 10-Deoxymethymycin + 2 Reduced Ferredoxin [Iron-Sulfur] Cluster + 2 H+ + O2 = Methymycin + 2 Oxidized Ferredoxin [Iron-Sulfur] Cluster + H2O;;(5) 10-Deoxymethymycin + 2 Reduced Ferredoxin [Iron-Sulfur] Cluster + 2 H+ + O2 = Neomethymycin + 2 Oxidized Ferredoxin [Iron-Sulfur] Cluster + H2O;;(6) 10-Deoxymethymycin + 4 Reduced Ferredoxin [Iron-Sulfur] Cluster + 4 H+ + 2 O2 = Novamethymycin + 4 Oxidized Ferredoxin [Iron-Sulfur] Cluster + 2 H2O，系统名称为Narbomycin,reduced Ferredoxin:oxygen Oxidoreductase (Pikromycin-Forming)，一种细胞色素 P-450（血红素-硫醇盐）蛋白。参与许多含去氧糖胺糖苷单元的细菌大环内酯类抗生素的生物合成。作用于 narbomycin 时，它在 C-12 位羟基化生成匹克罗霉素，或在 C-14 位羟基化生成新匹克罗霉素，或在两个位点同时羟基化生成 narvopikromycin。作用于 10-脱氧甲基霉素时，它在 C-10 位羟基化生成甲基霉素，或在 C-12 位羟基化生成新甲基霉素，或在两个位点同时羟基化生成 novamethymycin。
暂无数据！
扫码关注公众号
