产品内容
本酶催化的反应为(1) 4'-O-Methylnorbelladine + [Reduced NADPH---Hemoprotein Reductase] + O2 = (4AR,10bS)-Noroxomaritidine + [Oxidized NADPH---Hemoprotein Reductase] + 2 H2O;;(2) 4'-O-Methylnorbelladine + [Reduced NADPH---Hemoprotein Reductase] + O2 = (4AS,10bR)-Noroxomaritidine + [Oxidized NADPH---Hemoprotein Reductase] + 2 H2O,系统名称为4'-O-Methylnorbelladine,NADPH---Hemoprotein Reductase:oxygen Oxidoreductase (Noroxomaritidine-Forming),一种P-450(血红素-硫醇盐)酶。该酶已从黄水仙 Narcissus pseudonarcissus(黄水仙)中得到表征,通过催化分子内氧化对-对'酚偶联形成石蒜科生物碱降氧马替定宁的两种对映异构体。该氧化涉及分子氧但不将其掺入产物。