产品内容
本酶催化的反应为(1) 3-Oxocholan-24-Oyl-CoA + NAD+ = 3-Oxochol-4-En-24-Oyl-CoA + NADH + H+;;(2) 3-Oxochol-4-En-24-Oyl-CoA + NAD+ = 3-Oxochol-4,6-Dien-24-Oyl-CoA + NADH + H+;;(3) 12alpha-Hydroxy-3-Oxocholan-24-Oyl-CoA + NAD+ = 12alpha-Hydroxy-3-Oxochol-4-En-24-Oyl-CoA + NADH + H+;;(4) 12alpha-Hydroxy-3-Oxochol-4-En-24-Oyl-CoA + NAD+ = 12alpha-Hydroxy-3-Oxochol-4,6-Dien-24-Oyl-CoA + NADH + H+;;系统名称为3-Oxocholan-24-Oyl-CoA Delta4,6-Oxidoreductase，含有黄素。该酶源自细菌斯氏梭菌（Clostridium scindens），参与胆汁酸 7alpha-脱羟基途径。该酶催化 7alpha-脱水之后胆汁酸 A/B 环内双键的两次连续还原。
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