产品内容
本酶催化的反应为A [Protein] With Reduced L-Cysteine Residues + Thioredoxin Disulfide = A [Protein] Carrying A Disulfide Bond + Thioredoxin (Overall Reaction);;(1a) A [Thioredoxin:protein Disulfide Reductase] With Reduced L-Cysteine Residues + Thioredoxin Disulfide = A [Thioredoxin:protein Disulfide Reductase] Carrying A Disulfide Bond + Thioredoxin;;(1b) A [Thioredoxin:protein Disulfide Reductase] Carrying A Disulfide Bond + A [Protein] With Reduced L-Cysteine Residues = A [Thioredoxin:protein Disulfide Reductase] With Reduced L-Cysteine Residues + A [Protein] Carrying A Disulfide Bond，系统名称为Thioredoxin:protein Disulfide Oxidoreductase (Dithiol-Forming)，DsbD 蛋白存在于革兰氏阴性菌中，将电子从细胞质硫氧还蛋白转移到周质底物蛋白 DsbC、DsbG 和 CcmG，将靶蛋白中的二硫键还原为二硫醇。在革兰氏阳性菌中发现的 NrdH 氧化还原因子催化类似反应。
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