产品内容
本酶催化的反应为3 S-Adenosyl-L-Methionine + A [Histone H3]-L-Lysine79 = 3 S-Adenosyl-L-Homocysteine + A [Histone H3]-N6,N6,N6-Trimethyl-L-Lysine79 (Overall Reaction);;(1a) S-Adenosyl-L-Methionine + A [Histone H3]-L-Lysine79 = S-Adenosyl-L-Homocysteine + A [Histone H3]-N6-Methyl-L-Lysine79;;(1b) S-Adenosyl-L-Methionine + A [Histone H3]-N6-Methyl-L-Lysine79 = S-Adenosyl-L-Homocysteine + A [Histone H3]-N6,N6-Dimethyl-L-Lysine79;;(1c) S-Adenosyl-L-Methionine + A [Histone H3]-N6,N6-Dimethyl-L-Lysine79 = S-Adenosyl-L-Homocysteine + A [Histone H3]-N6,N6,N6-Trimethyl-L-Lysine79，系统名称为S-Adenosyl-L-Methionine:[histone H3]-L-Lysine79 N6-Trimethyltransferase，该酶连续甲基化组蛋白 H3 的 L-赖氨酸79 残基（H3K79），最终生成三甲基化形式。这些修饰影响染色质相关蛋白的结合。这是已知的唯一发生在组蛋白核心区域的赖氨酸甲基化事件，因为所有其他此类修饰都发生在尾部。
![天净沙[组蛋白H3]-赖氨酸79 N-三甲基转移酶活性测定试剂盒产品图片](https://www.tjs.bio/content/xtheme/tianjingsha/images/noimage.jpg)
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