Name: 天净沙透明质酸合酶活性测定试剂盒
Brand: 天净沙
SKU: 7-EC2.4.1.212
Availability: InStock

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天净沙透明质酸合酶活性测定试剂盒

英文名：Skygen Hyaluronan Synthase Assay Kit

别名：SpHAS; SeHAS; Alternating UDP-alpha-N-Acetyl-D-Glucosamine:beta-D-Glucuronosyl-(1->3)-[Nascent Hyaluronan] 4-N-Acetyl-beta-D-Glucosaminyltransferase And UDP-alpha-D-Glucuronate:N-Acetyl-beta-D-Glucosaminyl-(1->4)-[Nascent Hyaluronan] 3-beta-D-Glucuronosyltransferase

产品编号：7-EC2.4.1.212

保存温度：-20℃

运输温度：Cold

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7-EC2.4.1.212

100 T

3-4 Weeks

本酶催化的反应为(1) UDP-N-Acetyl-alpha-D-Glucosamine + beta-D-Glucuronosyl-(1->3)-N-Acetyl-beta-D-Glucosaminyl-(1->4)-[Nascent Hyaluronan] = UDP + N-Acetyl-beta-D-Glucosaminyl-(1->4)-beta-D-Glucuronosyl-(1->3)-N-Acetyl-beta-D-Glucosaminyl-(1->4)-[Nascent Hyaluronan];;(2) UDP-alpha-D-Glucuronate + N-Acetyl-beta-D-Glucosaminyl-(1->4)-beta-D-Glucuronosyl-(1->3)-[Nascent Hyaluronan] = UDP + beta-D-Glucuronosyl-(1->3)-N-Acetyl-beta-D-Glucosaminyl-(1->4)-beta-D-Glucuronosyl-(1->3)-[Nascent Hyaluronan]，系统名称为Alternating UDP-N-Acetyl-alpha-D-Glucosamine:beta-D-Glucuronosyl-(1->3)-[Nascent Hyaluronan] 4-N-Acetyl-beta-D-Glucosaminyltransferase And UDP-alpha-D-Glucuronate:N-Acetyl-beta-D-Glucosaminyl-(1->4)-[Nascent Hyaluronan] 3-beta-D-Glucuronosyltransferase (Configuration-Inverting)，来自 A 组和 C 组链球菌（Streptococcus）的酶需要 Mg2+。当非还原末端为 GlcA 时，该酶将 GlcNAc 添加到新生透明质酸上，但当非还原末端为 GlcNAc 时，它添加 GlcA [3]。该酶对 UDP-GlcNAc 和 UDP-GlcA 高度特异；如果任一被 UDP-Glc、UDP-Gal、UDP-GalNAc 或 UDP-GalA 替代，则观察不到共聚合。在多种生物中已发现类似酶。

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天净沙透明质酸合酶活性测定试剂盒

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