产品内容
本酶催化的反应为(1) 4-Amino-4-Deoxy-alpha-L-Arabinopyranosyl Ditrans,octacis-Undecaprenyl Phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-Lipid A = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-Lipid A + Ditrans,octacis-Undecaprenyl Phosphate;; (2) 4-Amino-4-Deoxy-alpha-L-Arabinopyranosyl Ditrans,octacis-Undecaprenyl Phosphate + Lipid IVA = Lipid IIA + Ditrans,octacis-Undecaprenyl Phosphate;; (3) 4-Amino-4-Deoxy-alpha-L-Arabinopyranosyl Ditrans,octacis-Undecaprenyl Phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-Lipid IVA = 4'-alpha-L-Ara4N-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-Lipid IVA + Ditrans,octacis-Undecaprenyl Phosphate,系统名称为4-Amino-4-Deoxy-alpha-L-Arabinopyranosyl Ditrans,octacis-Undecaprenyl-Phosphate:lipid IVA 4-Amino-4-Deoxy-L-Arabinopyranosyltransferase,一种存在于某些革兰氏阴性内生细菌内膜中的整合膜蛋白。在不产生 3-脱氧-D-甘露-辛酮糖酸(Kdo)的菌株中,该酶向四酰化脂质 A 前体(脂质 IVA)的 1-磷酸部分添加单个阿拉伯糖单位。在存在 Kdo 二糖的情况下,该酶主要向脂质 A 分子的 4-磷酸添加阿拉伯糖单位。鼠伤寒沙门菌 Salmonella typhimurium 的酶可以在两个位置都添加阿拉伯糖单位。