产品内容
本酶催化的反应为Selenophosphate + Geranyl Diphosphate + 5-Methylaminomethyl-2-Thiouridine34 In TRNA + H2O = 5-Methylaminomethyl-2-Selenouridine34 In TRNA + (2E)-3,7-Dimethylocta-2,6-Diene-1-Thiol + Diphosphate + Phosphate (Overall Reaction);;(1a) Geranyl Diphosphate + 5-Methylaminomethyl-2-Thiouridine34 In TRNA = 5-Methylaminomethyl-2-(S-Geranyl)thiouridine34 In TRNA + Diphosphate;;(1b) Selenophosphate + 5-Methylaminomethyl-2-(S-Geranyl)thiouridine34 In TRNA = 5-Methylaminomethyl-2-(Se-Phospho)selenouridine34 In TRNA + (2E)-3,7-Dimethylocta-2,6-Diene-1-Thiol;;(1c) 5-Methylaminomethyl-2-(Se-Phospho)selenouridine34 In TRNA + H2O = 5-Methylaminomethyl-2-Selenouridine34 In TRNA + Phosphate，系统名称为Geranyl Diphosphate/selenophosphate:tRNA 5-Methylaminomethyl-2-Thiouridine34 Geranyl/selenophosphatetransferase，这种细菌酶通过涉及香叶基化和随后所得香叶基化中间体的磷酸硒化的两步过程，将 5-甲基氨基甲基-2-尿苷和 5-羧甲基氨基甲基-2-尿苷转化为相应的硒代尿苷形式。所得的硒代磷酸化尿苷中间体进一步与水分子反应，释放磷酸根阴离子和 2-硒代尿苷 tRNA。该酶含有一个 rhodanese 结构域。
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