产品内容
本酶催化的反应为ATP + A Long-Chain Fatty Acid + Holo-[Mycocerosate Synthase] = AMP + Diphosphate + A Long-Chain Acyl-[Mycocerosate Synthase] (Overall Reaction);;(1a) ATP + A Long-Chain Fatty Acid = Diphosphate + A Long-Chain Acyl-Adenylate Ester;;(1b) A Long-Chain Acyl-Adenylate Ester + Holo-[Mycocerosate Synthase] = AMP + A Long-Chain Acyl-[Mycocerosate Synthase],系统名称为Long-Chain Fatty Acid:holo-[Mycocerosate Synthase] Ligase (AMP-Forming),该酶存在于某些分枝杆菌中,通过腺苷酰化活化长链脂肪酸并将其转移给 EC 2.3.1.111(分枝菌蜡酸合酶)。该酶参与毒力脂质二分枝菌蜡酸酯(DIM)和二分枝菌蜡酰三糖基酚肽枝蜡醇(PGL)的生物合成。