产品内容
本酶催化的反应为ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-Diphospho-Ditrans,octacis-Undecaprenol + L-Glutamine + H2O = ADP + Phosphate + beta-D-GlcNAc-(1->4)-MurNAc-L-Ala-D-Isoglutaminyl-L-Lys-D-Ala-D-Ala-Diphospho-Ditrans,octacis-Undecaprenol + L-Glutamate (Overall Reaction);;(1a) L-Glutamine + H2O = L-Glutamate + NH3;;(1b) ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-Diphospho-Ditrans,octacis-Undecaprenol = ADP + beta-D-GlcNAc-(1->4)-MurNAc-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala-Diphospho-Ditrans,octacis-Undecaprenol;;(1c) beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-Diphospho-Ditrans,octacis-Undecaprenol + NH3 = beta-D-GlcNAc-(1->4)-MurNAc-L-Ala-D-Isoglutaminyl-L-Lys-D-Ala-D-Ala-Diphospho-Ditrans,octacis-Undecaprenol + Phosphate，系统名称为beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-Diphospho-Ditrans,octacis-Undecaprenol:L-Glutamine Amidoligase (ADP-Forming)，该酶复合体存在于革兰氏阳性菌中，由两个亚基组成。谷氨酰胺酶亚基（参见 EC 3.5.1.2，谷氨酰胺酶）产生一个氨分子，被引导到连接酶亚基，后者将其添加到脂质 II 的活化 D-谷氨酸残基上，将其转化为异谷氨酰胺残基。
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